Symptoms of myeloma

Myeloma can cause a range of symptoms because of its effect on the bones, bone marrow, blood, urine and kidneys.

The most common symptoms of myeloma include:

• bone pain or a broken bone that has not been caused by an obvious injury
• frequent infections or an infection that is hard to shake off
• tiredness, shortness of breath or a racing heart, caused by a low level of red blood cells (anaemia)
• kidney problems, which may be caused by excess amounts of paraprotein produced by the myeloma cells. The symptoms of kidney problems may include frothy urine (wee or pee), passing too much or too little urine, nausea (feeling sick), weight loss or fluid retention (puffiness or swelling in the body)
• feeling sick, drowsy or confused, because of too much calcium in the blood (hypercalcaemia)
• abnormal blood counts, because myeloma cells may stop the bone marrow from making enough normal blood cells.

Other conditions can cause these symptoms, so these changes do not mean you definitely have myeloma. If you are worried or have ongoing symptoms, see your general practitioner (GP).

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