Research Type: Extramural
This study will explore whether certain microRNAS could be targeted in combination with chemotherapy to kill breast cancer cells and improve patient outcomes.
This research builds on previous findings that the protein MCL-1 acts like a life and death switch for triple negative breast cancer cells.
This project will determine how drug resistance develops at the genetic level and explore ways of making treatment approaches more effective.
Developing a world first radiation system to ensure the safe delivery of radiation doses to patients
This team is perfecting a new radiation dosimetry system that will detect and treat cancers as they move through the body.
This SPAR trial will test whether taking a statin for 3 months during and after cancer treatment improves the response of a rectal tumour to radiation and chemotherapy.
Using models of a bone cancer developed in the lab, Dr Kansara will investigate the effectiveness of targeting a specific immune protein, both alone and in combination with chemotherapy.
This project will provide the critical clinical evidence on the effectiveness of adding progesterone to antiestrogenic therapies in patients with early stage breast cancer.
This project will investigate how to hijack the stress-response techniques melanoma cells have developed to promote their survival.
The outcomes of this new study will be the identification of key players involved in the function of a protein called MCC and how they could be targeted in cancer treatment.
Genetically modified immune cells can be used to cure cases of leukaemia that are otherwise incurable. This project will optimise the technology to create cures for other types of cancer.