Cancer Council NSW logo
13 11 20 Information & Support
Give monthly
Menu
  • Cancer Information
    • By cancer type
      • Bowel cancer
      • Blood cancers
      • Breast cancer
      • Lung cancer
      • Melanoma
      • Prostate cancer
      • View 26 other cancers
    • General information
      • What is cancer?
      • When you are first diagnosed
      • Cancer treatment
      • Managing side effects
      • Living well
      • Practical concerns
      • Advanced cancer
    • How can we help you?
      • Carers
      • Family and friends
      • Multilingual cancer information
      • Schools and teachers
    • More resources
      • Understanding Cancer books
      • Podcast: The Thing About Cancer
      • Podcast: The Thing About Advanced Cancer
      • Cancer Information Services
      • Cancer information for Aboriginal & Torres Strait Islander people
  • Get Support
    • How can we help you
      • 13 11 20 – Speak to a cancer professional
      • Connect with others
      • Cancer Counselling
      • Pro Bono Program
      • Financial Assistance
      • Transport to cancer treatment
      • Accommodation during cancer treatment
      • Support for cancer survivors
    • More information
      • Information for health professionals
      • Aboriginal & Torres Strait Islander people
      • Multilingual cancer information
      • LGBTI
      • Cancer and COVID-19 in NSW
      • Webinars
  • Cancer Prevention
    • By topic
      • Alcohol
      • Diet and exercise
      • Screening and early detection
      • Smoking
      • Sun protection
    • Programs
      • SunSmart NSW website
      • Improve your long game
      • Tackling Tobacco
  • Research
    • By Topic
      • Research we conduct
      • Research we fund
      • Information for researchers
      • Community Involvement in Research
    • Quick links
      • Search research by cancer type or topic
      • Research Grant Applications
      • Research Achievements
  • Get Involved
    • How will you get involved
      • Volunteer with us
      • Work with us
      • Fundraise for us
      • Partner with us
      • Campaign with us
      • Shop with us
    • Quick Links
      • Events calendar
      • Request a Cancer Council Talk
      • Share your story
      • Supporter Recognition
  • Donate
    • Donate today
    • Donate monthly
    • Donate in memory
    • Leave a gift in your will
    • More ways to donate
  • Cancer Information
    • By cancer type
      • Bowel cancer
      • Blood cancers
      • Breast cancer
      • Lung cancer
      • Melanoma
      • Prostate cancer
      • View 26 other cancers
    • General information
      • What is cancer?
      • When you are first diagnosed
      • Cancer treatment
      • Managing side effects
      • Living well
      • Practical concerns
      • Advanced cancer
    • How can we help you?
      • Carers
      • Family and friends
      • Multilingual cancer information
      • Schools and teachers
    • More resources
      • Understanding Cancer books
      • Podcast: The Thing About Cancer
      • Podcast: The Thing About Advanced Cancer
      • Cancer Information Services
      • Cancer information for Aboriginal & Torres Strait Islander people
  • Get Support
    • How can we help you
      • 13 11 20 – Speak to a cancer professional
      • Connect with others
      • Cancer Counselling
      • Pro Bono Program
      • Financial Assistance
      • Transport to cancer treatment
      • Accommodation during cancer treatment
      • Support for cancer survivors
    • More information
      • Information for health professionals
      • Aboriginal & Torres Strait Islander people
      • Multilingual cancer information
      • LGBTI
      • Cancer and COVID-19 in NSW
      • Webinars
  • Cancer Prevention
    • By topic
      • Alcohol
      • Diet and exercise
      • Screening and early detection
      • Smoking
      • Sun protection
    • Programs
      • SunSmart NSW website
      • Improve your long game
      • Tackling Tobacco
  • Research
    • By Topic
      • Research we conduct
      • Research we fund
      • Information for researchers
      • Community Involvement in Research
    • Quick links
      • Search research by cancer type or topic
      • Research Grant Applications
      • Research Achievements
  • Get Involved
    • How will you get involved
      • Volunteer with us
      • Work with us
      • Fundraise for us
      • Partner with us
      • Campaign with us
      • Shop with us
    • Quick Links
      • Events calendar
      • Request a Cancer Council Talk
      • Share your story
      • Supporter Recognition
  • Donate
    • Donate today
    • Donate monthly
    • Donate in memory
    • Leave a gift in your will
    • More ways to donate
  • Home
  • Prostate cancer
  • Research
  • Towards more personalised prostate cancer treatment

Towards more personalised prostate cancer treatment

Professor Lisa Butler The University of Adelaide $433,228 2022-2024

Background

Prostate cancer is the most common cancer in Australian men. Thanks to advances in early detection and treatment in recent decades, around 95% of men diagnosed will survive beyond five years. However, once prostate cancer has spread the five-year survival rate drops dramatically to just 30%. Current treatments for advanced prostate cancer improve quality of life and extend survival, but relapses are common. New treatments are urgently needed to improve outcomes for men with advanced prostate cancer. 

The research

Professor Butler and her team are currently testing a new drug for prostate cancer in clinical trials. The drug, called ribociclib, targets two proteins that are overactive in cancer cells helping to drive cancer growth and spread. The drug was recently approved for use in advanced breast cancer, and in earlier laboratory testing Professor Butler and her team found that ribociclib was also effective in prostate cancer.  

In this project, alongside their clinical trials of ribociclib for prostate cancer, Professor Butler and her team will identify biomarkers that can be used to identify which patients this new drug is likely to benefit. Developing a companion test for these biomarkers will accelerate the translation of this research to a new personalised treatment option for men with advanced prostate cancer. 

The impact

This project will play a critical role in the use of ribociclib and its related drugs for advanced prostate cancer. Complemented by a companion biomarker test, the team hope their work will lead to the first personalised treatment of its kind for prostate cancer, offering new hope for the hundreds of men diagnosed with advanced stage disease each year. 

 

Search research
Cancer research depends on your support
Give monthly
Share

Achievements
18 Jun 2020

Addressing the needs of long-term prostate cancer survivors

Find out more
20 May 2020

HPV vaccine linked to decline in premature births

Find out more
Latest news
19 Jul 2021

ROSA – A roadmap for individualised breast screening

Find out more
  • About us
  • News & Media
  • Cancer Council Shop
  • Contact us
  • Work with us
  • Privacy and website policies
Aboriginal Daffodil logo

Cancer Council NSW acknowledges the traditional custodians of the land on which we live and work. We pay our respects to the elders past and present and extend that respect to all other Aboriginal and Torres Strait Islander peoples.

Registered Charity (ACNC)

© Cancer Council NSW 2021. Cancer Council NSW is registered with the Australian Taxation Office as an Income Tax Exempt Charity: Charitable Fundraising Authority No. 18521. ABN 51 116 463 846. Cancer Council NSW, 153 Dowling Street, Woolloomooloo NSW 2011. All donations over $2 are tax deductible.