Can microRNAs can be targeted to improve breast cancer treatment
Background
MicroRNAs are tiny molecules produced in every cell in the body. They are powerful controllers of gene expression, and this research team has shown that modulating microRNAs can have a significant therapeutic impact on breast cancer tissue in the laboratory. The researchers believe that microRNAs control the signally pathways that are central to breast cancer survival and drug response, which means that these molecules could be used in new approaches for cancer control.
The research
This study will explore the behaviour of microRNAs and determine how certain microRNAS could be targeted in combination with chemotherapy to kill breast cancer cells and improve patient outcomes. With their industry partners, the researchers are in a position to be able to progress their findings into studies with breast cancer patients.