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  • Boosting the immune system to help it find and kill lymphoma cells

Boosting the immune system to help it find and kill lymphoma cells

University of New South Wales 2017-2019

Background

T cells are a type of immune cell that have the ability to recognise and kill tumour cells. However, when tumours have grown too big, these T cells become inactive. This is a major obstacle to using immune-based therapies as a way to treat lymphoma. A better understanding of the mechanisms that lead to the inactivation of T cells is urgently needed so that strategies to overcome this inactivation can be developed.

The research

This research project will use a powerful microscope to identify how tumour cells deactivate T cells. The team will implement a special nanotechnology that could potentially ‘rescue’ these inactivated T cells so that they can continue to find and kill cancer cells.

The impact

Ultimately, this research could lead to a new form of cancer therapy that targets the immune system with minimal side effects for the patient.

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