Type: Bone cancer

Dr Michelle McDonald and her team are in a unique position to examine how some drugs help to keep cancer cells in bone at bay.

Test tubes

Dr Micklethwaite has been developing myeloma-specific CAR T-cells – immune cells specifically designed to recognise and destroy myeloma cells.

Professor Croucher and his team have demonstrated the potential of a newly approved treatment for osteoporosis to strengthen and rebuild bone damaged by myeloma.

Professor Watkins and his team have shown that osteosarcomas rely on a specific molecular pathway to grow. The team is now researching ways to block this pathway to stop tumour growth.

Using models of a bone cancer developed in the lab, Dr Kansara will investigate the effectiveness of targeting a specific immune protein, both alone and in combination with chemotherapy.