Topic: Childhood cancer

A/Professor Ziegler will test if a new drug combination can switch off the overactive molecular pathway and halt cancer progression in the most aggressive childhood brain tumours.

Dr Cheung’s project will be the first to identify and investigate the risk factors for the development of some childhood cancers.

Researchers will test a more targeted treatment approach in greatly improving outcomes for individual children with advanced neuroblastoma.

Prof Gottardo will test a new treatment they hope will provide the answer to minimising devastating side effects of medulloblastoma treatment.

Professor Liu and his team are investigating how particular proteins affect the development and growth of tumours in children with TERT-rearranged neuroblastoma.

This project aims to discover how a particular protein called BRD4 leads to the development and growth of tumours in children with TERT-rearranged neuroblastoma.

A synthetic retinoid (a compound derived from vitamin A) has been found to acts powerfully against Diffuse intrinsic pontine gliomas (DIPG) cells.

This study will compare current standard PCV treatment to oral temozolomide chemotherapy combined with with radiation, for effectiveness with fewer side effects.

Professor Murray Norris

The aim of this 5 year program is to increase survival rates of children with Acute Lymphoblastic Leukaemia (ALL) and ultimately develop prevention strategies.