Type: Brain cancer

A/Professor Ziegler will test if a new drug combination can switch off the overactive molecular pathway and halt cancer progression in the most aggressive childhood brain tumours.

Prof Gottardo will test a new treatment they hope will provide the answer to minimising devastating side effects of medulloblastoma treatment.

This research has provided a groundbreaking insight into the relationship between the protein dyskerin
and neuroblastoma, a deadly childhood cancer.

A synthetic retinoid (a compound derived from vitamin A) has been found to acts powerfully against Diffuse intrinsic pontine gliomas (DIPG) cells.

This study will compare current standard PCV treatment to oral temozolomide chemotherapy combined with with radiation, for effectiveness with fewer side effects.

A novel approach to shutting down the energy supply in cancer cells has led to highly promising treatments that are already undergoing successful trials in people with solid cancer tumours.

Dr Megan Chircop’s team have found new compounds that can target the deadliest type of malignant brain tumour, glioblastoma multiforme.