Targeted therapy for advanced melanoma
New types of drugs known as targeted therapy attack specific genetic mutations within cancer cells, while minimising harm to healthy cells. They are generally taken as tablets (orally). Targeted therapy is most commonly used for advanced melanoma that has spread to other organs or if the melanoma has come back after surgery.
Several different targeted therapy drugs have been approved for people who have the BRAF mutation. Drugs are often used together to help block the effects of the BRAF mutation and reduce the growth of the melanoma. Drugs for NRAS and C-KIT mutations may be available through clinical trials – talk to your doctor about whether you are a suitable candidate.
Cancer cells may become resistant to targeted therapy drugs over time. If this happens, your doctor will suggest trying another type of systemic therapy.
Learn more about:
Listen to podcasts on New Cancer Treatments – Immunotherapy and Targeted Therapy and Making Treatment Decisions
Side effects of targeted therapy
The side effects of targeted therapy will vary depending on which drugs you are given. Common side effects include fever, tiredness, loss of appetite, joint aches and pains, nausea, rash and other skin problems, diarrhoea, and high blood pressure. Ask your treatment team for advice about dealing with any side effects.
| It’s important to let your doctor know immediately of any side effects. If left untreated, some side effects can become serious. |
Video: What is targeted therapy?
Watch this short video to learn more about targeted and immunotherapy.
Click on the icon below to download a PDF booklet on targeted therapy
Instructions for downloading and reading EPUB files
Apple devices
The iBooks application must be installed on your Apple device before you can read the EPUB.
Different ways to download an EPUB file to your Apple device:
- email EPUB files to yourself and transfer the attachment to iBooks.
- copy EPUB files into DropBox (or a similar service) and use the DropBox app to send them to iBooks.
- open EPUB files directly from Mobile Safari and open them in iBooks, where they are saved automatically by downloading the EPUB from the website.
Need more help? Visit: http://support.apple.com/kb/HT4059
Kobo
To download an EPUB file to your Kobo from a Windows computer:
- download and save the EPUB directly onto your desktop.
- connect your Kobo to your computer using the USB cable and tap “Connect” on your eReader.
- select “Open folder to view files” to view the contents of your Kobo.
- navigate to where you have stored your EPUB file in “Finder”, in documents or downloads, and drag and drop it into the Kobo window. You can now disconnect your Kobo to read the eBook.
To download an EPUB to your Kobo from a Mac:
- download and save the EPUB directly onto your desktop.
- connect your Kobo to your computer using the USB cable and tap “Connect” on your eReader.
- open your “Finder” application.
- select “Kobo eReader” from the listed devices to view the contents of your Kobo.
- navigate to where you have stored your EPUB file in “Finder”, probably in documents or downloads, and drag and drop it into the Kobo window. You can now disconnect your Kobo to read the eBook.
Turn on your Kobo and your EPUB will be located in “eBooks”, while a PDF will be located in “Documents”.
Need more information? Visit: http://www.kobo.com/help/koboaura/response/?id=3784&type=3
Sony Reader
To download an EPUB file on your Sony Reader™:
- ensure you have already installed the Reader™ Library for PC/Mac software
- select the eBook you want from our website and click the link to download it.
- connect the Reader™ to your computer.
- open the Reader™ Library software and click “Library” in the left-hand pane and select the eBook to view it.
Need more help? Visit: https://au.readerstore.sony.com/apps_and_devices/
Amazon Kindle 2nd Generation devices
EPUB files can’t be read on the Amazon Kindle™. However, like most eReaders, Kindle™ 2nd Generation devices are able to display PDFs. We recommend that you download the PDF version of this booklet if you would like to read it on a Kindle™.
To transfer a PDF to your Kindle™ via USB cable from your computer or Mac:
- download the PDF directly onto your computer.
- connect the USB cable to your computer’s USB port, and the micro USB end of the cable to your Kindle™. Note: the Kindle™ won’t be available as a reading device while it is connected to your computer until it has been disconnected.
- open the Kindle™ drive and several folders will appear inside. The “Documents” folder is where you will need to copy or drag the PDF to.
- safely eject your Kindle™ from your computer and unplug the USB cable. Your content will appear on the Home Screen.
Kindle also provides a Kindle Personal Documents Service that allows users to send documents as an attachment directly to your eReader. For more information on this service, visit http://www.amazon.com/gp/help/customer/display.html/ref=help_search_1-1?ie=UTF8&nodeId=200767340&qid=1395967989&sr=1-1
For more information on accessing a PDF on your Kindle™, visit www.amazon.com/manageyourkindle, log in to your account and click on Personal Document Settings.
Need more help? Visit https://www.amazon.com/gp/help/customer/display.html?nodeId=200375630
Android and PC
You can also download and open eBooks on Android devices and PCs with appropriate apps or software installed. Suitable eReader apps for Android include Google Play Books, FBReader and Moon+ Reader. Suitable software for PCs include Calibre and Adobe Digital Editions.
This information was last reviewed in January 2019
Support services
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Work and cancer
Information for employees, employers and workplaces dealing with cancer
Cancer information
Making treatment decisions for advanced cancer
Weighing up the benefits and side effects of treatment
Using targeted therapies
Information about drug therapies and immunotherapies
Where to find clinical trials
Links to information about current clinical trials of new therapies
